Table 1.
Characteristics of patients listed for SLK in the United States from May 1st 2007 to July 1st 2014 under the old policy alone, the new policy alone, both policies, or neither policy.
| Non-SLK (n=35 012) |
O-SLK (n=2452) |
N-SLK (n=1638) |
B-SLK (N=1878) |
P value |
|
|---|---|---|---|---|---|
| Days on waitlist, m(IQR) | 197 (28 – 799) | 33 (12 – 83) | 288 (160 – 627) | 377 (182 – 803) | <0.001 |
| Age at delisting, m(IQR) | 56 (50 – 62) | 57 (51 – 62) | 59 (54 – 65) | 59 (53 – 64) | <0.001 |
| Female sex, no (%) | 13 050 (37) | 881 (36) | 843 (52) | 730 (39) | <0.001 |
| Listing diagnosis, no. (%) | |||||
| Alcohol | 7630 (22) | 613 (25) | 262 (16) | 356 (19) | <0.001 |
| HCV | 13 077 (37) | 852 (35) | 615 (38) | 765 (41) | |
| NAFLD/NASH | 7060 (20) | 613 (25) | 483 (30) | 476 (25) | |
| Autoimmune1 | 4815 (14) | 181 (7) | 220 (13) | 118 (6) | |
| Other | 2429 (7) | 193 (8) | 58 (4) | 163 (9) | |
|
Non-Hispanic white, no. (%) |
25708 (73) | 1622 (66) | 1216 (74) | 1087 (58) | <0.001 |
| Ascites, no. (%) | 13214 (38) | 1441(59) | 920 (56) | 940 (50) | <0.001 |
| Diabetes, no. (%) | 7516 (22) | 814 (33) | 509 (31) | 846 (45) | <0.001 |
|
Hepatic encephalopathy, no. (%) |
5740 (16) | 609 (25) | 469 (29) | 328 (18) | <0.001 |
|
MELDNa at listing, m(IQR) |
19 (14 – 26) | 29 (22 – 36) | 18 (15 – 23) | 21 (19 – 24) | <0.001 |
|
MELDNa at delisting, m(IQR) |
23 (15 – 32) | 32 (25 – 39) | 34 (28 – 40) | 26 (22 – 33) | <0.001 |
|
Final CKD-EPI eGFR, ml/min, m(IQR)* |
69 (42 – 97) | 32 (20 – 45) | 22 (17 – 26) | 18 (12 – 23) | <0.001 |
|
Final MDRD4 eGFR, ml/min, m(IQR)* |
71 (46 – 98) | 33 (21 – 45) | 23 (18 – 27) | 19 (13 – 24) | <0.001 |
|
Final serum creatinine, mg/dL, m(IQR)* |
1.1 (0.8 – 1.5) | 2.1 (1.6 – 3.1) | 2.7 (2.2 – 3.3) | 3.3 (2.7 – 4.6) | <0.001 |
|
Hemodialysis at Delisting, no. (%) |
3235 (9) | 1425 (58) | 792 (48) | 1385 (74) | <0.001 |
| Waitlist Outcome, no. (%) | <0.001 | ||||
| Still Waiting | 9915 (28) | 220 (9) | 143 (8) | 419 (22) | |
| ”Too Sick” or Death | 9140 (26) | 751 (31) | 631 (39) | 717 (38) | |
| DDLT | 15 956 (46) | 1481 (60) | 864 (53) | 742 (40) |
Table Legend: Hepatitis C (HCV); Nonalcoholic Steatohepatitis (NASH); CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration); Modification of Diet in Renal Disease (MDRD); Estimated Glomerular Filtration Rate (eGFR); International Normalized Ratio (INR); Model for End-Stage Liver Disease including Sodium (MELDNa); median (m); interquartile range (IQR)
1
autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis
*
excludes those on hemodialysis