Table 1.
Anthropometric and biochemical parameters of study population
| Parameter (reference interval or cut-off) | Controls (n= 37) | PCOS patients (n = 36) | P-value | ||
|---|---|---|---|---|---|
|
|
|
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| Mean (SD) | Range | Mean (SD) | Range | ||
| Age (years) | 28.3 (9.2) | 18–45 | 27.8 (7.3) | 16–43 | n.s. |
| Height (m) | 1.6 (0.1) | 1.5–1.75 | 1.6 (0.1) | 1.5–1.76 | n.s. |
| Weight (kg) | 59.3 (7.7) | 46–83 | 82.5 (13.9) | 56–116 | <0.0001 |
| BMI (<29.9 kg/m2) | 22.2 (2.6) [10.8] | 18.4–29.8 | 31.5 (5.6) [88.8] | 20–43.7 | <0.0001 [<0.0001] |
| WC (<80 cm) | 74.2 (8.4) [20.6] | 52–93.5 | 98.4 (14.2) [88.9] | 78–135 | <0.0001 [<0.0001] |
| Glucose (<100 mg/dL) | 87.6 (8.7) [5.6] | 74–111 | 89.7 (11.8) [8.3] | 74–137 | n.s. [n.s.] |
| Insulin (4.0–23.5 microun/mL) | 9.4 (3.7) [0] | 4.58–21 | 15.5 (9.6) [14.3] | 2–52 | 0.002 [n.s.] |
| HOMA (<2.5) | 2 (0.8) [27.8] | 0.98–4 | 3.6 (2.6) [65.7] | 0.45–11.5 | 0.003 [0.006] |
| Total cholesterol (<200 mg/dL) | 180.4 (34.4) [20] | 142–283 | 197.1 (31) [42.4] | 142–272 | 0.04 [n.s.] |
| Triglycerides (<150 mg/dL) | 71.0 (60.7) [6.7] | 22–351 | 121.1 (57.6) [20.6] | 43–265 | 0.001 [n.s.] |
| HDL cholesterol (>50 mg/dL) | 58.7 (11.2) [11.1] | 44–94 | 56.9 (15.4) [45.5] | 30–87 | [n.s.] [0.009] |
| LDL cholesterol (<130 mg/dL) | 113.4 (30.8) [16.7] | 73.2–209.4 | 108.9 (38.1) [22.9] | 0–186.6 | n.s. [n.s.] |
Data are reported as means (SDs), percentage of altered values are reported in squared brackets. Significance: p<0.05.
BMI, body mass index; HOMA, Homeostasis Model Assessment; n.s., not significant; PCOS, polycystic ovary syndrome; WC, waist circumference.