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. 2019 Feb 6;39(6):1077–1087. doi: 10.1523/JNEUROSCI.1596-18.2018

Figure 3.

Figure 3.

Context-induced relapse to alcohol seeking is associated with selective activation of the AI. Outline of the experimental procedure (A). Number of Fos-positive neurons per square millimeter in the AI in rats tested in Context A: alcohol context, or in Context B: punishment context who were either low relapsing or high relapsing. Correlation between alcohol seeking behavior in Context B: punishment context and active lever presses on relapse test (B). Photomicrographs representing Fos-protein expression across each treatment group (C). Data are presented as mean ± SEM. n = 6–8/group. Scale bar, 200 μm. **p < 0.01 versus Alcohol group, #p < 0.05 versus Punishment high relapsing group, *p < 0.05.