Table 1.
Characteristics of TCRS Participants with Serum CC16 and Lung Function Data Available at Different Surveys
| Year 11 (n = 540) | Year 16 (n = 425) | Year 22 (n = 424) | Year 26 (n = 321) | Year 32 (n = 248) | |
|---|---|---|---|---|---|
| Serum CC16, ng/ml, geometric mean (n) | 7.52 (540) | 8.50 (425) | 11.21 (424) | 9.52 (321) | 10.63 (248) |
| Age, yr, mean ± SD (n) | 10.7 ± 0.561 (539) | 16.5 ± 0.552 (420) | 21.8 ± 0.681 (423) | 26.3 ± 0.678 (319) | 31.7 ± 1.01 (248) |
| Male, % (n) | 49.4 (267) | 50.4 (214) | 48.6 (206) | 47.7 (153) | 44.4 (110) |
| Parental ethnicity, % (n) | |||||
| NHW/NHW | 58.2 (314) | 60.2 (256) | 62.5 (265) | 62.0 (199) | 60.9 (151) |
| NHW/Hispanic | 14.3 (77) | 13.4 (57) | 14.6 (62) | 14.0 (45) | 12.9 (32) |
| Hispanic/Hispanic | 14.3 (77) | 12.2 (52) | 11.6 (49) | 11.8 (38) | 12.9 (32) |
| Other | 13.3 (72) | 14.1 (60) | 11.3 (48) | 12.2 (39) | 13.3 (33) |
| BMI, mean ± SD (n) | 19.1 ± 3.98 (540) | 23.2 ± 5.45 (425) | 25.7 ± 6.68 (424) | 27.4 ± 7.69 (321) | 29.1 ± 8.91 (248) |
| Height, cm, mean ± SD (n) | 145 ± 8.20 (540) | 170 ± 9.30 (425) | 171 ± 9.68 (424) | 172 ± 10.0 (321) | 171 ± 10.3 (248) |
| Active smoking, % (n/N) | |||||
| Nonsmoking | 98.0 (432/441) | 69.1 (282/408) | 44.6 (189/424) | 43.0 (137/319) | 44.4 (110/248) |
| Current | 0.23 (1) | 10.3 (42) | 29.0 (123) | 25.7 (82) | 16.1 (40) |
| Former | 1.81 (8) | 20.6 (84) | 26.4 (112) | 31.4 (100) | 39.5 (98) |
| Active asthma, % (n/N) | 16.1 (86/533) | 21.3 (89/417) | 19.0 (80/422) | 21.0 (66/315) | 20.2 (50/248) |
| Maternal age, yr, mean ± SD (n) | 27.5 ± 4.56 (540) | 27.6 ± 4.35 (425) | 27.7 ± 4.54 (424) | 27.3 ± 4.77 (321) | 27.6 ± 4.37 (248) |
| Mother smoked at Year 6, % (n/N) | 19.5 (103/529) | 18.1 (76/420) | 17.5 (72/412) | 18.7 (58/311) | 19.1 (46/241) |
| Parental education, % (n/N) | |||||
| Both >12 yr | 62.6 (329/526) | 65.2 (272/417) | 65.6 (274/418) | 66.4 (211/318) | 66.5 (163/245) |
| Only mother >12 yr | 9.89 (52) | 8.87 (37) | 9.33 (39) | 10.1 (32) | 10.2 (25) |
| Only father >12 yr | 8.56 (45) | 10.1 (42) | 9.33 (39) | 8.81 (28) | 8.98 (22) |
| Neither >12 yr | 19.0 (100) | 15.8 (66) | 15.8 (66) | 14.8 (47) | 14.3 (35) |
Definition of abbreviations: BMI = body masss index; CC16 = club cell secretory protein 16; NHW = non-Hispanic white; TCRS = Tucson Children’s Respiratory Study.