TABLE 1.
Distribution of histopathological lesions in sham- and PCV3-inocuated piglets
| Group | Inoculum | No. positive/no. tested (avg score)a for: |
||||||
|---|---|---|---|---|---|---|---|---|
| Lung | Liver | Lymph nodes | Spleen | Kidney | Heart | Small intestines | ||
| Experiment 1 | ||||||||
| 1 | Sham | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) |
| 2 | PCV3b | 5/5 (2.8) | 5/5 (1.8) | 5/5 (2.8) | 5/5 (2.6) | 5/5 (2.6) | 4/5 (1.6) | 5/5 (2.2) |
| 3 | PCV3-KLHb | 5/5 (3.0) | 5/5 (2.4) | 5/5 (3.0) | 5/5 (2.8) | 5/5 (2.8) | 5/5 (2.2) | 5/5 (2.6) |
| Experiment 2 | ||||||||
| 1 | Sham | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) | 0/5 (0.0) |
| 2 | PCV3 | 5/5 (2.6) | 5/5 (1.8) | 5/5 (2.6) | 5/5 (2.2) | 5/5 (2.2) | 4/5 (1.6) | 5/5 (2.2) |
a
Average histological scores for organs and tissues: 0, normal; 1, mild; 2, moderate; 3, severe.
b
All the remaining piglets from each group were necropsied at 28 dpi, and a total of four dead piglets from groups 1 and 2 were also included in histopathological evaluation.