FIG 4.

RhCMV Rh05 is conserved in Old World monkey CMV species. An alignment of the predicted amino acid sequence of Rh05 with putative homologues of cynomolgus CMV 31908 (CyCMV), simian CMV Colburn (SCMV), Baboon CMV OCOM4-37 (BaCMV), and Drill monkey CMV OCOM6-2 (DrCMV) was generated using the CLUSTAL O (1.2.4) multiple sequence alignment tool. Highlighted are the predicted signal sequence (green, predicted using the SignalP 4.1 server), transmembrane region (blue, predicted using the Phobius server), and potential glycosylation sites (red, using the NetNGlyc 1.0 server). In addition, amino acids that that have been defined as conserved across the RL11 family of proteins are circled in black.