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. 2019 Feb 5;93(4):e01457-18. doi: 10.1128/JVI.01457-18

TABLE 2.

List of cell lines used in experimental systems

Cell line Description Reference
HepG2 HLA-A*02:01+, HCC line with no HBV DNA integration
HepG2-hNTCP-A3 (A3 clone) HepG2 cells overexpressing HBV entry receptor (hNTCP) 14
HepG2.2.15 HepG2 cells with full HBV genome integration producing virions 10
HepG2-Env HepG2 cells transduced with HBV Env 35
PLC/PRF5-HLA-A*02:01 Natural HCC line with partial HBV surface antigen DNA integration; transduced with the HLA-A*02:01 molecule 36
EBV core HLA-A*02:01+, EBV immortalized B cell lines transduced with HBV core DNA 8
HepAD38 HepG2 cells with full HBV genome integration producing virions 40