TABLE 1.
Nucleotide and amino acid identity between donor template (C4 and B5 strains) and acceptor template (C2 strain)a
| EV-A71 strain | Sequence type | Identity (%) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall | VP4 | VP2 | VP3 | VP1 | 2A | 2B | 2C | 3A | 3B | 3C | 3D | ||
| C4 | Nucleotide | 83.3 | 88.9 | 91.3 | 91.9 | 90.5 | 84.9 | 74.7 | 79.0 | 76.4 | 75.8 | 75.8 | 77.9 |
| Amino acid | 96.7 | 100.0 | 100.0 | 99.6 | 98.7 | 97.3 | 92.9 | 96.7 | 94.2 | 90.9 | 94.0 | 93.9 | |
| B5 | Nucleotide | 80.1 | 80.7 | 81.2 | 82.0 | 83.1 | 81.2 | 75.8 | 79.7 | 78.1 | 80.3 | 77.3 | 79.1 |
| Amino acid | 95.5 | 100.0 | 97.6 | 97.1 | 97.3 | 96.7 | 91.9 | 95.7 | 93.0 | 95.5 | 91.8 | 93.7 | |
a
Consensus sequences of the C4 and B5 subgenotypes were used to perform the pairwise sequence alignments with the C2 acceptor template strain. The EV-A71 full-genome sequences used to calculate the consensus are described by Lee et al. (22). The sequence identities at the RNA and amino acid levels are denoted as percentages. Boldfacing indicates sequence identities at the RNA level to the C2 acceptor template in the region where recombination can occur.