FIG 3.
Interactions between Fab AT12-015 and HPeV3. (A) Fab binds to an epitope extended across neighboring asymmetric units in the assembled virion. Viral capsid residues that participate in Fab heavy (VH) and light (VL) chain binding are highlighted in yellow and are reported in the accompanying table. (B) Stabilizing interactions at the interface. Residues that form hydrogen bonds or a salt bridge are highlighted in yellow on the left, and colored by chain on the enlarged inset on the right. In the inset, hydrogen bonds are shown as black dashed lines along with a centrally located salt bridge highlighted in red.