TABLE 2.
Amino acid sequence identity analysis of consensus GP vaccines
| Consensus vaccine | % amino acid sequence identity to GP reference sequence at the indicated MLD residues |
||||||
|---|---|---|---|---|---|---|---|
| EBOV |
BDBV |
SUDV |
|||||
| Residues 389–403 | Residues 401–415 | Residues 477–491 | Residues 349–364 | Residues 484–499 | Residues 313–367 | Residues 469–495 | |
| EC1 | 40.00 | 26.67 | 33.33 | 56.25 | 68.75 | 50.91 | 51.85 |
| EC2 | 33.33 | 26.67 | 33.33 | 37.50 | 68.75 | 50.91 | 51.85 |
| ECHI | 40.00 | 26.67 | 33.33 | 56.25 | 68.75 | 50.91 | 51.85 |
| ECM | 40.00 | 26.67 | 33.33 | 56.25 | 68.75 | 50.91 | 51.85 |
| EC1J | NAa | NA | NA | NA | 37.50 | NA | 3.70 |
| EC1O | NA | NA | NA | NA | NA | NA | NA |
a
NA, not applicable since EC1J and EC1O lack the mucin-like domain (MLD).