Figure 5.

Summary of positive predictions supported by the literature

A. Literature analysis of the positive predictions for cell line HepG2. A positive prediction can be “Verified as POS” if interaction evidence is found in published literature (green); “Verified as NEG” if evidence is found that there is no interaction between members (red); or it can be “Unverified” if no evidence is found for either case (blue). B. Database cross-check of verified positive predictions for cell line HepG2. “Not in any database” (red) means that the predicted interactions are not found in either CORUM or BioGRID; blue indicates the number of positive predictions not found in BioGRID, whereas orange indicate the number of positive predictions not found in CORUM. Green slice indicates the number of predictions found in at least one of the two databases. C. Positive predictions literature analysis for cell line K562 (same color code as A). D. Database cross-check of verified positive predictions for cell line K562 (same color code as B). pred., predictions.