Table 2.
PREF CBT | PREF PAT | RAND CBT | RAND PAT | Total | |
---|---|---|---|---|---|
BDI | |||||
Baseline | |||||
Score, mean (SD) | 32.0 (7.8) | 31.2 (7.8) | 32.6 (7.0) | 33.9 (9.2) | 32.1 (8.0) |
n | 63 | 101 | 41 | 47 | 252 |
Year 1 (t4) | |||||
Difference, mean (SD) | 14.4 (12.1) | 10.7 (11.1) | 12.6 (13.3) | 12.0 (12.7) | 12.1 (12.0) |
Cohen’s d | 1.58 | 1.09 | 1.20 | 1.00 | 1.17 |
Remission, % | 38 | 28 | 47 | 32 | 34 |
n | 37 | 76 | 34 | 38 | 185 |
Year 2 (t6) | |||||
Difference, mean (SD) | 15.2 (9.7) | 13.9 (12.7) | 11.9 (12.2) | 15.2 (12.7) | 14.1 (12.0) |
Cohen’s d | 1.77 | 1.38 | 1.03 | 1.39 | 1.38 |
Remission, % | 45 | 38 | 33 | 33 | 38 |
n | 31 | 61 | 27 | 30 | 149 |
Year 3 (t8) | |||||
Difference, mean (SD) | 17.2 (10.7) | 15.8 (10.9) | 17.5 (12.4) | 20.1 (11.9) | 17.2 (11.4) |
Cohen’s d | 2.43 | 1.62 | 1.85 | 1.89 | 1.83 |
Remission, % | 43 | 44 | 50 | 44 | 45 |
n | 28 | 64 | 30 | 27 | 149 |
QIDS-C | |||||
Baseline | |||||
Score, mean (SD) | 14.1 (3.0) | 14.3 (3.0) | 13.3 (2.6) | 15.2 (3.4) | 14.3 (3.1) |
n | 63 | 101 | 41 | 47 | 252 |
Year 1 (t4) | |||||
Difference, mean (SD) | 7.1 (4.0) | 5.7 (4.4) | 6.6 (4.8) | 6.8 (4.9) | 6.4 (4.5) |
Cohen’s d | 1.90 | 1.46 | 1.92 | 1.39 | 1.56 |
Remission, % | 54 | 33 | 41 | 33 | 39 |
n | 41 | 69 | 34 | 40 | 184 |
Year 2 (t6) | |||||
Difference, mean (SD) | 7.8 (4.5) | 8.0 (4.4) | 6.9 (5.9) | 8.6 (4.9) | 7.9 (4.8) |
Cohen’s d | 2.12 | 2.45 | 1.62 | 1.94 | 2.07 |
Remission, % | 57 | 44 | 46 | 44 | 47 |
n | 35 | 64 | 28 | 34 | 161 |
Year 3 (t8) | |||||
Difference, mean (SD) | 7.0 (5.5) | 8.0 (5.1) | 9.7 (3.7) | 10.4 (5.9) | 8.5 (5.2) |
Cohen’s d | 1.69 | 1.85 | 3.43 | 2.38 | 2.08 |
Remission, % | 52 | 55 | 79 | 68 | 61 |
n | 33 | 71 | 33 | 28 | 165 |
BDI, Beck Depression Inventory II; CBT, cognitive-behavioural therapy; PAT, psychoanalytic therapy; PREF, preference arm; QIDS-C, clinician-rated Quick Inventory of Depressive Symptoms; RAND, randomization arm. Shown are mean baseline scores and standard deviations, as well as means and standard deviations of difference scores compared to baseline for participants 1, 2, and 3 years after baseline (‘improvement’ on BDI/QIDS-C scale). Effect sizes (Cohen’s d) were estimated by subtracting patients’ scores (1, 2, 3 years) from their baseline scores, divided by the square root of pooled variance. Remission rates (BDI ≤12, QIDS-C ≤5) and number of participants with full data at each time point are also reported.