Destruction of epithelium and glands |
|
Morphologically normal |
0 |
Focal destruction of the epithelial surface and/or focal crypt dropout |
1 |
Zonal destruction of the epithelial surface and/or zonal crypt loss |
2 |
Diffuse and/or mucosal ulceration involving submucosa and/or diffuse crypt losses |
3 |
Dilatation of glandular crypts |
Normal |
0 |
Focal dilatation |
1 |
Zonal dilatation |
2 |
Dilated crypts |
3 |
Depletion and loss of goblet cells |
|
Normal |
0 |
Slightly depleted goblet cells |
1 |
Zonal or moderately depleted goblet cells |
2 |
Diffusely or completely depleted goblet cells |
3 |
Inflammatory cell infiltration |
Absence of infiltrate |
0 |
Infiltrate at the subepithelial and lamina propria level or crypt bases |
1 |
Infiltrate reaching muscularis mucosae |
2 |
Severe and extensive infiltrate reaching submucosa and/or involving muscularis propria |
3 |
Edema |
Absent |
0 |
Focal |
1 |
Zonal and/or moderately diffuse |
2 |
Extensive or severe |
3 |
Vascular congestion |
Absent |
0 |
Focal |
1 |
Zonal |
2 |
Diffuse |
3 |
Crypt abscesses |
Absent |
0 |
Focal |
1 |
Zonal |
2 |
Diffuse |
3 |
Atrophia |
Absent |
0 |
Focal |
1 |
Zonal |
2 |
Diffuse |
3 |