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. 2018 Dec 21;17(3):1841–1846. doi: 10.3892/etm.2018.7126

Figure 3.

Figure 3.

miR-761 regulates CRC cell proliferation and migration through targeting Rab3D. (A) Reverse transcription-quantitative polymerase chain reaction was used to analyze miR-761 expression in the SW480 cell line with the miR-mimic or NC transfection. (B) Western blotting was used to analyze Rab3D expression in the SW480 cell line with miR-mimic and pCMV-Rab3D co-transfection. (C) Cell Counting kit-8 assay was used to analyze cell proliferation in the SW480 cell line with the miR-mimic and pCMV-Rab3D transfection. (D) Wound-healing assay to analyze cell migration following miR-mimic and pCMV-Rab3D transfection. (E) A schematic diagram demonstrating the miR-761/Rab3D axis in CRC progression. **P<0.01 and ***P<0.001 vs. the NC group. ns vs. the NC group. ns, not significant; miR-761, microRNA-761; CRC, colorectal cancer.