Table 3:

Neutralization ID₅₀ values obtained with sera from wk0 and and wk22 in a standard TZMbl assay. Pre immune sera failed to neutralize any of the tested viruses.

Group	Group details	Animal ID	Bleed Week	Neutralization ID50
				SVA-MLV Neg. Ctrl.	MN.3 Clade B Tier 1	JR-FL Clade B Tier 2	SF162.LS Clade B Tier 1	MW965.26 Clade C Tier 1
1	particles conjugated to b122a-19iC for prime, full length JRFL gp120 for boost	#874	22	12	118	<10	62	23
		#875	22	<10	13	<10	39	<10
		#876	22	<10	16	<10	11	11
		#877	22	<10	53	<10	10	13
2	particles displaying b122a for prime, full length JRFL gp120 for boost	#878	22	14	15	11	<10	15
		#879	22	<10	29	<10	14	20
		#880	22	<10	28	<10	18	<10
		#881	22	12	11	<10	<10	10
3	particles displaying ODec for prime, full length JRFL gp120 for boost	#882	22	<10	4502	<10	179	23
		#883	22	<10	21	<10	11	11
		#884	22	<10	56	<10	<10	12
		#885	22	11	12	<10	830	64
4	particles displaying b122a1-b for prime, full length JRFL gp120 for boost	#886	22	12	351	<10	1149	108
		#887	22	<10	427	<10	74	24
		#888	22	12	121	40	615	576
		#889	22	14	19	20	17	<10
5	particles conjugated to b122a-19iC (ADJUPLEX) for prime, full length JRFL gp120 for boost	#890	22	<10	376	<10	238	187
		#891	22	<10	737	<10	35	40
		#892	22	<10	49	<10	18	152
		#893	22	11	14	<10	764	1111
6	empty particles for prime, full length JRFL gp120 for boost	#894	22	<10	10	<10	<10	<10
		#895	22	<10	17	<10	45	<10
		#896	22	<10	17	<10	<10	23
		#897	22	<10	20	<10	19	<10