Table 4:
Sera competition binding studies using ELISA.
| Percent competition at 1:50 dilution of week 22 seraa | |||||
|---|---|---|---|---|---|
| b12 | F105 | VRC-PG04 | VRC01 | PGT128 | |
| Group1 | 10±2 | 38±1 | 9±2 | 14±2 | 2±1 |
| Group2 | 12±0.5 | 26±2 | 14±1 | 12±1 | 4±2 |
| Group3 | 17±2 | 28±2 | 22±1 | 11±1 | 14±1 |
| Group4 | 42±2b | 57±1b | 26±2 | 21±1 | 15±1 |
| Group5 | 21±2 | 29±1 | 26±1 | 18±2 | 14±1 |
| Group6 | 19±0.5 | 18 | 14±1 | 18±1 | 4±1 |
a
Data shown represent percent competition from two independent experiments and are represented as mean±SE.
b
Percent competition for Group 4 sera with antibodies b12 and F105 is significantly higher compared to other groups, P<0.01 (individual means compared by Welch’s t-test).