Table 3.

Drugs-resistance mutations according to HIV-1 subtypes and time of diagnosis in drug-naïve individuals from Paraná State, Brazil, 2010–2013

Sample identification	Diagnosis	HIV-1 subtype	NRTI mutations	NNRTI mutations	PI mutations	Resistance [23, 24]
L19	Chronic	B	–	K101E	–	EFV, NVP, ETR, RPV
L39	Chronic	C	–	K103 N	–	EFV, NVP
L97	Chronic	B	T215S	–	–	ZDV, d4T
L99	Recent	B	D67 N, T215S	–	–	ZDV, d4T, ABC
L150	Chronic	B	D67G	–	–	–
L156	Chronic	B	K70R	–	–	DDI, ZDV, d4T
L168	Chronic	C	–	G190E	–	EFV, NVP
M6	Chronic	C	–	K103 N	–	EFV, NVP
M18	Recent	B	–	K103 N	–	EFV, NVP
M19	Chronic	B	–	–	I54 V, V82A	IDV, NFV, LPV/r

HIV-1 human immunodeficiency virus type 1, PR protease, RT reverse transcriptase, PI protease inhibitors, NRTI nucleoside analogue reverse transcriptase inhibitor, NNRTI non-nucleoside analogue reverse transcriptase inhibitors, EFV efavirenz, NVP nevirapine, ETR etravirine, RPV rilpivirine, ZDV zidovudine, d4T stavudine, ABC abacavir, DDI didanosine, IDV indinavir, NFV nelfinavir, LPV/r lopinavir/ritonavir