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. 2019 Feb 6;19:29. doi: 10.1186/s12890-019-0791-0

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Changes in MUC5AC after CD147 silencing by siRNA transfection. CD147 protein (a) and mRNA (b) expression levels were assessed after siRNA transfection. Three CD147 siRNA were designed, and CD147 siRNA 1 was the most effective at silencing CD147 expression. *p < 0.05, compared with control transfection. MUC5AC secretion (c) and MUC5AC mRNA expression (d) were detected after CD147 silencing. **p < 0.05, compared with the control group, ***p < 0.05, compared with the 10% CS extract group. The results are representative of 3 independent experiments