Table 4.

Overarching recommendations for fostering innovation in symptom management

No.	Recommendation
1.	Develop definitions for individual symptoms accounting for culturally divergent patient experiences.
2.	Develop validated and standardized measures for individual symptoms to accurately assess burden.
3.	Conduct research to better understand the biologic basis for these symptoms in patients on dialysis.
4.	Conduct clinical trials of promising treatments including drugs, devices, and behavioral therapy.
5.	Test modifying dialysis care delivery to support and seamlessly integrate evidence-based treatments.
6.	Demonstrate the effect of symptoms on patient-reported and clinical outcomes.
7.	Advocate for payment reform that incentivizes improved treatment and management of symptoms.
8.	Perform focused prioritization and gap assessments among patients on peritoneal dialysis and patients on home-based hemodialysis.