Table 1.
Top 10 GO terms for each of the three annotation categories in axon-enriched proteins
Category | Term | Count | P-value |
---|---|---|---|
Biological Process | vesicle-mediated transport | 97 | 2.6×10−31 |
protein localization | 106 | 2.2×10−22 | |
generation of precursor metabolites and energy | 60 | 2.5×10−22 | |
protein transport | 94 | 1.1×10−21 | |
establishment of protein localization | 94 | 2.0×10−21 | |
intracellular transport | 85 | 7.0×10−20 | |
membrane organization | 63 | 7.4×10−20 | |
cellular carbohydrate catabolic process | 31 | 6.7×10−19 | |
alcohol catabolic process | 30 | 7.9×10−18 | |
glucose catabolic process | 27 | 9.5×10−18 | |
Molecular Function | cytoskeletal protein binding | 79 | 8.3×10−24 |
nucleotide binding | 195 | 1.1×10−17 | |
purine ribonucleotide binding | 164 | 1.9×10−16 | |
ribonucleotide binding | 164 | 2.0×10−16 | |
purine nucleotide binding | 169 | 2.5×10−16 | |
guanyl nucleotide binding | 58 | 7.5×10−15 | |
guanyl ribonucleotide binding | 58 | 7.5×10−15 | |
GTP binding | 56 | 1.6×10−14 | |
identical protein binding | 81 | 5.5×10−14 | |
actin binding | 46 | 1.5×10−13 | |
Cellular Component | Cytosol | 220 | 6.0×10−58 |
Cytoskeleton | 153 | 9.5×10−29 | |
soluble fraction | 77 | 1.1×10−26 | |
Mitochondrion | 175 | 3.6×10−25 | |
pigment granule | 36 | 5.8×10−23 | |
Melanosome | 36 | 5.8×10−23 | |
cytoskeletal part | 117 | 6.4×10−23 | |
neuron projection | 88 | 1.8×10−22 | |
cell projection | 119 | 2.9×10−22 | |
Vesicle | 106 | 1.2×10−20 |
Rank was based on the p-value.