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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Mol Neurobiol. 2018 Jul 28;56(4):2703–2713. doi: 10.1007/s12035-018-1266-7

Table 3.

Axon-enriched proteins related to axonal growth

Diseases or Functions Annotation p-value Molecules
axonogenesis 1.99×10−26 ACTB, APC, CASP3, GDI1, LLGL1, LRP4, MAP2K1, MBP, PTPRZ1, RAB10, RAB3A, RAB8A, RAP1B, STMN1, STXBP5, UCHL1, RUFY3, GSK3B, SNAP91
growth of axons 1.78×10−19 BRSK1, DCX, NES, ROCK2
guidance of axons 2.71×10−15 ALCAM, CDH2, TUBB3, CELSR3, CNTN1, CNTN2, DPYSL5, EPHA5, GLI3, KIF5C, MAPK1, MAPK3, MYH10, NRXN1, NRXN3, TENM2
outgrowth of axons 2.04×10−14 PLXNA3, PTPRS, SPRR1A, SYN1, VAMP2, VIM, GPM6A, ROBO1, KIF3C
branching of axons 1.12×10−10 A2M, ACTR3, APP, CDC42, EZR, GAP43, KALRN, KIF2A, L1CAM, MTOR, NRP1, PALM, PDIA3
elongation of axons 4.70×10−8 CDK5, PAFAH1B1, PPP2CA, STMN2
length of axons 2.97×10−7 CLASP2, KRAS, DPYSL3, RAC1, RHOA
shape change of axons 1.15×10−6 RTN4, SOD1, DCC, DPYSL2
morphology of axons 6.03×10−6 CD47, CKB, DCLK1, GPM6B, KIDINS220, MAP1B, MAPT, NCAM1, NFASC, NRCAM, PPP3CA, SH3GL1, SH3GL2, VCAN
quantity of axons 6.58×10−6 APOE, BAX, CANX, NEFM, FYN, KIF5A

Rank was based on the p-value.