Table 3.
Epidemiology of invasive pneumococcal disease (IPD) in adults ≥65 years of age before (1998–1999) and after (2004) the introduction of 7-valent pneumococcal conjugate vaccine (PCV7) in young children in 2000.
| 1998–1999 | 2004 | |||
|---|---|---|---|---|
| Pneumococcal serotypes | No. of IPD cases per 100,000 population | Percentage of all IPD cases | No. of IPD cases per 100,000 population | Percentage of all IPD cases |
| All | 61.5 | 100 | 38.0 | 100 |
| 7 Serotypes in PCV7 (which are also in PPV) | 34.5 | 56 | 8.2 | 22 |
| 16 Serotypes in PPV but not in PCV7 | 17.2 | 28 | 18.7 | 49 |
| All 23 serotypes in PPV | 51.7 | 84 | 26.9 | 71 |
| Serotypes not in PPV | 9.8 | 16 | 11.1 | 29 |
NOTE. PPV, pneumococcal polysaccharide vaccine. Data adapted from Hicks et al. [38].