Table 2.
Category | Clinical marker | n | r | 95% CI | P-value |
---|---|---|---|---|---|
Inflammation | White blood cell count | 115 | 0.39 | 0.22, 0.53 | <0.001 |
ESR | 72 | 0.28 | 0.05, 0.48 | 0.017 | |
C-reactive protein | 115 | 0.43 | 0.27, 0.57 | <0.001 | |
Immunoglobulin G | 59 | −0.01 | −0.27, 0.25 | 0.93 | |
Serum amyloid A | 31 | 0.67 | 0.41, 0.83 | <0.001 | |
Liver function | ALT | 114 | −0.05 | −0.23, 0.13 | 0.13 |
Renal function | eGFR | 113 | −0.11 | −0.29, 0.08 | 0.26 |
Creatinine | 114 | 0.20 | 0.02, 0.37 | 0.034 | |
Complement | Complement factor C3 | 48 | 0.52 | 0.28, 0.70 | <0.001 |
Complement factor C4 | 47 | 0.52 | 0.27, 0.70 | <0.001 | |
CH50 | 31 | 0.30 | −0.06, 0.59 | 0.10 | |
Autoantibody | Rheumatoid factor | 50 | −0.06 | −0.34, 0.22 | 0.66 |
Anti-nuclear antibody | 89 | −0.04 | −0.24, 0.17 | 0.74 | |
C-ANCA | 51 | 0.40 | 0.14, 0.61 | 0.0039 | |
P-ANCA | 56 | 0.29 | 0.03, 0.51 | 0.031 | |
ACPA | 70 | 0.25 | 0.01, 0.45 | 0.040 | |
Anti-dsDNA antibody | 32 | −0.16 | −0.49, 0.20 | 0.37 | |
Coagulation | Fibrinogen | 25 | 0.38 | −0.02, 0.67 | 0.065 |
d-dimer | 40 | 0.09 | −0.23, 0.39 | 0.58 | |
Others | Albumin | 26 | −0.16 | −0.51, 0.25 | 0.45 |
Ferritin | 43 | −0.02 | −0.32, 0.28 | 0.87 | |
Immune complex | 27 | −0.30 | −0.61 0.09 | 0.13 | |
MMP3 | 66 | −0.12 | −0.36, 0.12 | 0.32 |
n: number; r: Pearson’s correlation coefficient; CI: confidence interval; ESR: erythrocyte sedimentation rate; CH50: 50% hemolytic activity of complement; ACPA: anti-cyclic citrullinated peptide antibody; dsDNA: double-stranded DNA; MMP3: matrix metalloproteinase 3.