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. 2018 Aug 28;31(1):23–32. doi: 10.1093/intimm/dxy056

Table 2.

Correlations between levels of FCN1 and clinical markers

Category Clinical marker n r 95% CI P-value
Inflammation White blood cell count 115 0.39 0.22, 0.53 <0.001
ESR 72 0.28 0.05, 0.48 0.017
C-reactive protein 115 0.43 0.27, 0.57 <0.001
Immunoglobulin G 59 −0.01 −0.27, 0.25 0.93
Serum amyloid A 31 0.67 0.41, 0.83 <0.001
Liver function ALT 114 −0.05 −0.23, 0.13 0.13
Renal function eGFR 113 −0.11 −0.29, 0.08 0.26
Creatinine 114 0.20 0.02, 0.37 0.034
Complement Complement factor C3 48 0.52 0.28, 0.70 <0.001
Complement factor C4 47 0.52 0.27, 0.70 <0.001
CH50 31 0.30 −0.06, 0.59 0.10
Autoantibody Rheumatoid factor 50 −0.06 −0.34, 0.22 0.66
Anti-nuclear antibody 89 −0.04 −0.24, 0.17 0.74
C-ANCA 51 0.40 0.14, 0.61 0.0039
P-ANCA 56 0.29 0.03, 0.51 0.031
ACPA 70 0.25 0.01, 0.45 0.040
Anti-dsDNA antibody 32 −0.16 −0.49, 0.20 0.37
Coagulation Fibrinogen 25 0.38 −0.02, 0.67 0.065
d-dimer 40 0.09 −0.23, 0.39 0.58
Others Albumin 26 −0.16 −0.51, 0.25 0.45
Ferritin 43 −0.02 −0.32, 0.28 0.87
Immune complex 27 −0.30 −0.61 0.09 0.13
MMP3 66 −0.12 −0.36, 0.12 0.32

n: number; r: Pearson’s correlation coefficient; CI: confidence interval; ESR: erythrocyte sedimentation rate; CH50: 50% hemolytic activity of complement; ACPA: anti-cyclic citrullinated peptide antibody; dsDNA: double-stranded DNA; MMP3: matrix metalloproteinase 3.