Spheroid Viability: (A) Microscope images of untreated and treated spheroids: (a) cells treated with 4 μM of 5-FU, (b) cells treated with 7 μM of 5-FU, (c) cells treated with 11 μM of 5-FU, (d) cells treated with 15 μM of 5-FU, (e) cells treated with 4 μM of 5-FUChnps7, (f) cells treated with 7μM of 5-FUChnps7, (g) cells treated with 11μM of 5FUChnps7, (h) cells treated with 15 μM of 5-FUChnps7, (B) Percent cell viability against tumor spheroids treated with varying concentrations of 5FU or 5-FUChnps7 after 48 hours (CTR = control; spheroids exposed to only culture medium), (C) Comparison of percent cell viability and corresponding tumor spheroids treated with same concentrations of 5-FU or 5-FUChnps7 after 48 hours.