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. 2018 Dec 5;294(5):1554–1567. doi: 10.1074/jbc.RA118.006128

Figure 1.

Figure 1.

Structural model of converter mutations in myosin V. A, diagram of the domain structure of myosin and the movement of the lever arm in the pre- and post-power–stroke states (L50, lower 50-kDa domain; U50, upper 50-kDa domain; CNV, converter domain; NT, N-terminal domain). B, an alignment of pre- and post-power–stroke state crystal structures showing the conformational change of the converter/lever arm. Navy, pre-power–stroke state structure (PDB code 1BR4); orange, post-power–stroke state structure (PDB code 1OE9); beige, light chain; green, converter domain.