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Detection of APP and APP cleavage products by immunoblotting
| Products | Size | Mouse α-APP (clone W0-2) | Rabbit α-APP (clone Y188) |
|---|---|---|---|
| kDa | |||
| Mature glycosylated APP695 | ∼98 | ✓ | ✓ |
| Immature glycosylated APP695 | ∼77 | ✓ | ✓ |
| sAPPα (residues 1–612 of APP695) | ∼89 | ✓ | Χ |
| sAPPβ (residues 1–596 of APP695) | ∼87 | Χ | Χ |
| β-CTF/C99 | ∼11 | ✓ | ✓ |
| α-CTF/C83 | ∼9 | Χ | ✓ |
