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. 2018 Dec 4;294(5):1502–1515. doi: 10.1074/jbc.RA118.005657

Figure 8.

Figure 8.

Model of aSec system transport. GspB traffics (1) and binds directly (2) to the cell membrane via electrostatic interactions with anionic lipids, where it subsequently interacts with SecA2 (3). Asp1 to Asp3 docked at the membrane, in concert, promote engagement of SecA2 with the entire AST domain of GspB to initiate transport (4).