Figure 3.

Contributions of the APP1, DPP1, LPP1, and PAH1 genes to the PA phosphatase activity and lipid content in yeast. Cells expressing or lacking the indicated gene (+ and −, respectively) were examined for PA phosphatase (PAP) activity (A) or for lipid (TAG and phospholipids) content (B). The PA phosphatase in yeast cells, which is elevated in the stationary phase, is contributed by the APP1, DPP1, LPP1, and PAH1 genes. The quadruple mutant with deletions in all four genes lacks detectable PA phosphatase activity. Cells with the deletion of PAH1 exhibit a massive reduction in TAG content. The data were taken from Ref. 67.