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. Author manuscript; available in PMC: 2019 Feb 6.
Published in final edited form as: Curr Alzheimer Res. 2014;11(7):655–663. doi: 10.2174/1567205011666140812114037

Fig. (3). IVIG does not affect the expression levels of total tau.

Fig. (3).

A) The immunoblot shows that TBS-extractable total tau levels appear to be equivalent in hippocampal lysates from mice treated with placebo and IVIG for six months. Note that levels of the β-actin loading control are also equivalent in the same samples. On the other hand, tau proteins bearing the AT-180 epitope appear reduced in the IVIG samples compared to placebo. B) Quantitative analysis revealed that total tau levels were unchanged between the two treatment groups (not shown), and that hippocampal levels of AT-180 were reduced by ~50% in IVIG relative to placebo. n = 6/group; *, p< 0.01 via Student’s unpaired t test (two-tailed).