Table 3.

Two by two tables for cell line A375 using knockdown experiments for finding edges, compared to TRANSFAC and JASPAR from Enrichr. When using the unaltered data and looking at edges with posterior probability of 0.5 or greater, 41 of the 302 candidate edges are found in TRANSFAC and JASPAR, and 14 of the 81 candidate edges at a cutoff of 0.95 are true edges. Similarly, when using the MCDC-corrected data, 63 of the 463 candidate edges at a cutoff of 0.5 are true edges and 20 of the 119 at a cutoff of 0.95 are true edges. Approximate binomial p-values are included.

		T&J
		cutoff: 0.5		cutoff: 0.95
		Yes	No	Yes	No
Unaltered	Yes	41	261	14	67
	No	4152	38836	4179	39030
		p-value: 0.02		p-value: 0.02
MCDC	Yes	63	400	20	99
	No	4130	38697	4173	38998
		p-value: 0.004		p-value: 0.01