Skip to main content
. 2019 Jan 25;15(1):e1007489. doi: 10.1371/journal.ppat.1007489

Fig 1. LANA forms nuclear bodies that colocalize with DAXX and EZH2, but not PML.

Fig 1

(A-B) BCBL1 cells were imaged by indirect immunofluorescence with antibodies to LANA (red) and (A) DAXX (green), or (B) EZH2 (green) or merge with Dapi (blue). Scale bar = 10 μm. (C) Schematic of the RFP-LANA fusion integrated into the endogenous LANA of the KSHV BAC16 genome. (D-G) Stable iSLK cells with BAC16 expressing RFP-LANA (red) were imaged by indirect immunofluorescence with antibodies to (D) DAXX (green), (E) EZH2 (green), (F) H3K27me3 (green), or (G) PML (green). Cells were counter-stained with Dapi (blue) as shown in merge. Scale bar = 10 μm.