Table 2. Infection type and hospital course among n = 779 first serious infection hospitalizations.
SOFA = Sequential Organ Failure Assessment. MEDS = Mortality in Emergency Department Sepsis. ICU-intensive care unit.
| Variable | PCSK9 variant present (n = 14) |
PCSK9 variant absent (n = 765) |
P value |
|---|---|---|---|
| Infection Type (n = 779) | < .001 | ||
| Lung | 7 (50.0%) | 311 (40.7%) | |
| Kidney | 2 (14.3%) | 150 (19.6%) | |
| Abdominal | 0 (0.0%) | 120 (15.7%) | |
| Skin | 1 (7.1%) | 102 (13.3%) | |
| Sepsis | 4 (28.6%) | 35 (4.6%) | |
| Other | 0 (0.0%) | 47 (6.1%) | |
| Hospital Course Variables | |||
| SOFA Score (median, IQR) | 1 (1–2) | 1 (0–2) | .26 |
| MEDS score (median, IQR) | 11 (6–15) | 9 (6–11) | .35 |
| ICU admission (n = 779) | 3 (21.4%) | 56 (7.3%) | .05 |
| Outcomes | |||
| Sepsis Hospital Death | 1 (7.1%) | 46 (6.0%) | .86 |
| 30-day case fatality | 4 (28.6%) | 145 (19.0%) | .37 |