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. Author manuscript; available in PMC: 2019 Oct 15.
Published in final edited form as: Eur J Pharm Sci. 2018 Aug 8;123:502–514. doi: 10.1016/j.ejps.2018.08.008

Fig. 3: Accuracy of predictions from Obach (1999) using the well-stirred model.

Fig. 3:

The accuracy is examined using: A) the traditional model with fu,B only; B) both fu,B and fu,inc; and C) no binding terms assuming fu,B and fu,inc cancel. The shaded area highlights predictions falling within two fold of observed values.