Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 15;54(3):869–878. doi: 10.3892/ijo.2019.4687

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Selmin et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

As^III induces BRCA1 and ESR1 CpG methylation in MCF7 cell mammary tumor xenografts. Bars are from 5 animals/group from 2 separate experiments (n=10) and represent the means (fold-change of MCF7 Control xenograft) ± SEM for (A) BRCA1 and ERα mRNA expression; (B) BRCA1 and ESR1 CpG methylation. Different letters represent statistically significant multiple comparison (a>b>c) differences (P<0.05). As^III, trivalent arsenite; BRCA1, breast cancer 1; ESR1, estrogen receptor 1; ERα, estrogen receptor-α.