Table I.
MAF1 expression and clinicopathological factors of patients with colorecetal cancer.
| Factor | Positive (n=97) Number (%) | Negative (n=49) Number (%) | P-value |
|---|---|---|---|
| Age (mean ± SD) | 63.8±1.35 | 67.8±1.56 | 0.0544 |
| Sex | |||
| Male | 60 (61.9) | 32 (65.3) | 0.6827 |
| Female | 37 (38.1) | 17 (34.7) | |
| Histological grade | |||
| tub1, tub2, pap | 87 (89.7) | 45 (91.8) | 0.6738 |
| por, muc | 10 (10.3) | 4 (8.2) | |
| Depth of tumor invasion | |||
| Tis, T1, T2 | 36 (37.1) | 31 (63.3) | 0.0027a |
| T3, T4 | 61 (62.9) | 18 (36.7) | |
| Lymph node metastasis | |||
| Absent | 61 (62.9) | 44 (89.8) | 0.0003a |
| Present | 36 (37.1) | 5 (10.2) | |
| Lymphatic invasion | |||
| Absent | 32 (33.0) | 23 (47.0) | 0.2139 |
| Present | 64 (66.0) | 25 (51.0) | |
| No data | 1 (1.0) | 1 (2.0) | |
| Venous invasion | |||
| Absent | 67 (69.1) | 39 (79.6) | 0.2890 |
| Present | 29 (29.9) | 9 (18.4) | |
| No data | 1 (1.0) | 1 (2.0) | |
| Distant metastasis | |||
| Absent | 83 (85.6) | 47 (95.9) | 0.0417a |
| Present | 14 (14.4) | 2 (4.1) | |
| Stage | |||
| 0, I, II | 57 (58.8) | 44 (89.8) | 0.0011a |
| IIIa, IIIb, IV | 40 (41.2) | 5 (10.2) | |
a
P<0.05. MAF1, MAF1 homolog, negative regulator of RNA polymerase III; muc, mucinous adenocarcinoma; pap, papillary adeno carcinoma; por, poorly differentiated adenocarcinoma; SD, standard deviation; Tis, tumor in situ; tub1, well differentiated tubular adeno carcinoma; tub2, moderately differentiated tubular adenocarcinoma.