Table III.
Univariate and multivariate survival analyses evaluating miR‐3664‐5P expression influencing cancer specific survival in gastric cancer (n=100).
| Variables | Univariate
|
Multivariate analysis
|
||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Sex | 0.880 | NA | ||
| Male | 1 | |||
| Female | 0.945 (0.458-1.952) | |||
| Age, years | 0.362 | NA | ||
| ≤50 | 1 | |||
| >50 | 0.700 (0.325-1.507) | |||
| Differentiation | 0.006b | 0.024a | ||
| Well/moderately | 1 | 1 | ||
| Poor | 2.625 (1.310-5.260) | 2.257 (1.114-4.573) | ||
| Clinical stage | 0.536 | NA | ||
| I-II | 1 | |||
| III-IV | 1.245 (0.622-2.493) | |||
| Tumor size, cm | 0.163 | NA | ||
| ≤3.5 | 1 | |||
| >3.5 | 1.641 (0.818-3.288) | |||
| Lymph node metastasis | 0.150 | NA | ||
| No | 1 | |||
| Yes | 1.663 (0.832-3.326) | |||
| T classification | 0.790 | NA | ||
| T1-T2 | 1 | |||
| T3-T4 | 1.009 (0.550-2.196) | |||
| miR-3664-5P expression | 0.003b | 0.010b | ||
| Low | 1 | 1 | ||
| High | 0.334 (0.163-0.686) | 0.380 (0.183-0.791) | ||
All of the results were adjusted using Cox proportional hazards models for differentiation and miR-3664-5P expression.
a
P<0.05;
b
P<0.01. NA, not adopted; HR, hazards ratio; CI, confidence interval; miR, microRNA.