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. 2019 Jan 17;54(3):807–820. doi: 10.3892/ijo.2019.4689

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Overexpression of miR-98 suppresses cell migration and invasion via inhibiting cellular epithelial-mesenchymal transition. (A) SO-RB50 and Y79 cells were transfected with miR-98 mimics or NC, and cell invasion was evaluated using a Transwell invasion assay (magnification, ×200). (B) Wound healing assay was conducted to determine cell migration in SO-RB50 and Y79 cells transfected with miR-98 mimics or NC (magnification, ×200). (C) Expression of epithelial marker E-cadherin, and the mesenchymal markers N-cadherin, fibronectin and vimentin in SO-RB50 and Y79 cells following transfection with miR-98 mimics or NC were analyzed. Data are presented as the mean ± standard error of three independent experiments. ^**P<0.01 vs. NC. miR, microRNA; NC, negative control.