Figure 6.

Electron microscopy of cardiomyocytes in rats. In the control group, the cardiomyocytes had a normal morphology. In exposed rats, broken cardiac muscle fibers and dissociated intercalated discs were observed. The mitochondrial membrane was swollen, pyknotic and partially cavitated, while the mitochondria appeared to exhibit vacuolization, and the mitochondrial cristae were broken or absent. Histological alterations appeared to increase as the dose increased. Black arrows indicate intercalated disc dissociation. bw, body weight.