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. 2018 Dec 31;43(3):1229–1240. doi: 10.3892/ijmm.2018.4045

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Copyright: © Du et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Measurement of Bax, Bcl-2 and caspase-3 protein expression in that cardiomyocytes of rats following exposure to silica nanoparticles. (A) Representative immunohistochemical images of Bax, Bcl-2 and caspase-3 proteins are presented (magnification, ×200). (B) Quantification of the number of cells expressing these proteins in the cardiomyocytes of rats. ^aP<0.05 vs. control group; ^bP<0.05 vs. 2 mg/kg·bw group. Bax, apoptosis regulator BAX; Bcl-2, apoptosis regulator Bcl-2; bw, body weight.