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Docking poses of compound 15 in the binding site of the (A) wild-type (PDB ID, 5CAV) and (B) mutant (PDB ID, 5CAS) EGFR domain; compound 20 in (C) the wild-type and (D) mutant EGFR domain and compound 35 in (E) the wild-type and (F) mutant EGFR domain. EFGR, epidermal growth factor receptor.
