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. 2018 Dec 20;43(3):1193–1202. doi: 10.3892/ijmm.2018.4037

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Characterization of AQP4 expression in the astrocytic compartment of the control and NBO treatment rat brains at 48 h. Triple immunofluorescent staining of GFAP (green), AQP4 (40) and DAPI (blue). (A) The immunofluorescence of AQP4(+)/GFAP(+) expression in the control and NBO treatment groups. (B) The quantification of AQP4(+)/GFAP(+) immunofluorescence in the control and NBO treatment rats group (3-5 fields was observed). ^*P<0.05 vs. the control group; ^#P<0.001 vs. the 60% NBO group. Scale bars, 50 µm. Arrow head, co-expression of AQP4(+)/GFAP(+) astrocytes; NBO, normobaric oxygen; AQP4, aquaporin-4; GFAP, glial fibrillary acidic protein.