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. 2018 Dec 20;43(3):1193–1202. doi: 10.3892/ijmm.2018.4037

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Characterization of NHE1 in the astrocytic compartment and effect of NBO on NHE1 expression astrocytes activation at 48 h. Triple immunofluores-cent staining of GFAP (green), NHE1 (40) and DAPI (blue). (A) The immunofluorescence of NHE1(+)/GFAP(+) expression in the control and NBO treatment groups. (B) The quantification of NHE1(+)/GFAP(+) immunofluorescence in control and NBO treatment rat groups (3-5 fields was observed). ^*P<0.05 vs. the control group; ^#P<0.05 vs. the 60% NBO group; Scale bars, 50 µm. Arrow head, co-expression of NHE1(+) and GFAP(+) astrocytes. NBO, normobaric oxygen; NHE1, Na⁺/H⁺exchanger 1; GFAP, glial fibrillary acidic protein.