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. 2019 Jan 21;43(3):1321–1330. doi: 10.3892/ijmm.2019.4071

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Copyright: © Ren et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of FGF-21 on expression levels of mTOR and Vps34. (A) Western blot analysis of mTOR and p-mTOR in H9c2 cardiomyocytes. The quantification of (B) mTOR/GAPDH and (C) p-mTOR/GAPDH. (D) Western blot analysis of Vps-34 in H9c2 cardiomyocytes. (E) Quantification of Vps34/GAPDH. ^*P<0.05 vs. control group, ^#P<0.05 vs. H/R group and ^&P<0.05 vs. H/R + FGF-21 group. Values are presented as mean ± standard deviation. Experiments were repeated in triplicate. FGF-21, fibroblast growth factor-21; H/R, hypoxia/reoxygenation; 3-MA, 3-methyladenine; mTOR, mechanistic target of rapamycin; p, phosphorylated.