Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 21;43(3):1430–1440. doi: 10.3892/ijmm.2019.4069

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Cai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

TLR4 interference reverses the effects of the FimA fusion protein on PBMC proliferation. (A) The expression levels of TLR4 mRNA were detected by reverse transcription quantitative polymerase chain reaction following treatment of PBMCs with or without siTLR4 transfection. Cell proliferation was detected by Cell Counting Kit-8 following treatment of PBMCs with 2, 4 and 6 μg/ml FimA fusion protein for (B) 12, (C) 24 and (D) 48 h and transfection with siTLR4. Data are expressed as the means ± standard deviation based on at least three independent experiments; ^*P<0.05 vs. the control group (negative siRNA-transfected). TLR4, toll-like receptor 4; FimA, Porphyromonas gingivalis fimbriae; PBMC, peripheral blood mononuclear cells; si, small interfering.