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. Author manuscript; available in PMC: 2019 Jun 21.
Published in final edited form as: Nat Genet. 2018 Dec 21;51(1):51–62. doi: 10.1038/s41588-018-0303-9

Figure 1. Study design schematic.

Figure 1.

Flowchart depicting strategy for the three association analysis strategies (common, rare, and exonic variants), as well as replication selection criteria and numbers of samples and SNPs by stage. Subsequent TWAS and PheWAS analyses using common variant summary statistics are also presented. SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; SNP, single nucleotide polymorphism; ICBP, International Consortium for Blood Pressure; BP-ICE, Blood Pressure-International Consortium for Exomechip; BioVU, Vanderbilt University biorepository; ADE, adverse drug events