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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Hum Pathol. 2018 Aug 17;83:1–6. doi: 10.1016/j.humpath.2018.08.004

Figure 1:

Figure 1:

Histopathologic and immunohistochemical features of an HNF1A mutated HCC arising in a background of LFABP deficient hepatic adenomatosis. A) and B) An area of hepatic adenoma has retained reticulin framework while C) and D) show an are of carcinoma arising in the hepatic adenoma that has loss of the reticulin framework. E) The borders of the adenoma are ill-defined with the neoplastic hepatocytes on the bottom half of the photo, and F) LFABP is diffusely lost in the adenoma and retained in the non-neoplastic hepatocytes in the lower left corner of the image (A,C, E: H&E 200x original magnification; B, D: reticulin stain 200x original magnification; F: LFABP immunohistochemical stain, Abcam, 200x original magnification)