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. 2019 Jan 28;103(2):291–298. doi: 10.1097/TP.0000000000002384

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Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Measurement of in vivo myocardial oxidative metabolism based on the C-11 clearance rate under a high cardiac work state induced by catecholamine stimulation (n = 3 each for infarcted porcine without cell therapy, infarcted porcine receiving induced pluripotent SC-derived cardiomycocytes (iPS-CM) sheets, infarcted porcine receiving skeletal myoblast (SM) sheets, and infarcted porcine receiving mesnchymal stem cell sheets). A, Acetate clearance rate (k-mono) as a measure of global cardiac oxygen consumption. B, CE increased by up to 21% in the hearts transplanted with the iPS-CM sheets (^#P < 0.05 vs baseline; *P < 0.05 vs other groups).