FIGURE 5.

Induced pluripotent SC-derived cardiomycocytes (iPS-CM) therapy enhances vasculogenic response. Vascular and arteriole densities were evaluated 2 months after cell therapy in sections from the IZ in the hearts of animals from the (A) induced pluripotent SC-derived cardiomycocytes (iPS-CM), (B) skeletal myoblast (SM), (C) mesnchymal stem cell, and (D) control groups by immunofluorescence labeling of SMA (red) and CD31 (green). E, Vascular density was determined by counting the CD31+ vascular structures. F, Arteriole density was determined by counting the vascular structures expressing both CD31 and SMA (*P < 0.05). Scale bar, 50 μm.