Table 1.
Biochemical test results after 20 months of drug treatment in ADPKD miniature pigs
| Parameters | CON | 2DG | MET | COM |
|---|---|---|---|---|
| BUN (mmol·L−1) | 6.07 ± 0.90 | 4.86 ± 0.32 | 5.12 ± 0.17 | 5.14 ± 0.32 |
| SCr (μmol·L−1) | 149.73 ± 10.43 | 108.70 ± 10.87* | 106.63 ± 20.20* | 109.67 ± 3.02* |
| P/C (mg·mmol−1) | 20.16 ± 3.86 | 8.64 ± 4.70 | 4.58 ± 0.82* | 4.87 ± 0.88* |
| ALT (U·L−1) | 50.07 ± 7.82 | 57.1 ± 25.68 | 51.83 ± 0.81 | 50.27 ± 5.19 |
| AST (U·L−1) | 28.7 ± 0.98 | 46 ± 16.44 | 32.87 ± 7.66 | 36.2 ± 6.3 |
n = 8. ALT, serum alanine aminotransferase; AST, serum aspartate aminotransferase; BUN, blood urea nitrogen; SCr, serum creatinine; P/C, urinary protein/creatinine ratio.