Figure 5.

miR-195 Improved the Outcome of Hemorrhagic Stroke in Rats

(A) miR-195 treatment improved the Garcia score in the rats of hemorrhagic stroke; n = 32 for NC-miR, n = 31 for miR-195. (B) Reduced brain edema; n = 9 for NC-miR, n = 7 for miR-195. (C) Reduced percentage of lesion volume; n = 14 for NC-miR, n = 15 for miR-195. (D) Reduced blood-brain barrier (BBB) permeability; n = 9 for NC-miR, n = 9 for miR-195. (E) Schematic showing the effects of miR-195 on neurovascular protection. Values are presented as mean ± SEM from three independent experiments performed in triplicate. *p < 0.05, **p < 0.01, and ***p < 0.001. All values were expressed as mean ± SE.